he effect of Bird Flu on humans

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The effect of Bird Flu on humans

Of the 15 subtypes known, only subtypes H5, H7 and H9 are known to be capable of crossing the species barrier from birds to humans. It is feared that if the avian influenza virus undergoes antigenic shift with a human influenza virus, the new subtype created could be both highly contagious and highly lethal in humans. Such a subtype could cause a global influenza pandemic, similar to the Spanish Flu that killed over 20 million people in 1918 (though a variety of sources quote average figures even higher, up to 100 million in some cases).

Many health experts are concerned that a virus that mutates to the point where it can cross the species barrier (i.e. from birds to humans) will inevitably mutate to the point where it can be transmitted from human to human. It is at that point that a pandemic becomes likely.

The first cases of avian influenza passed from birds to humans was H5N1 in 1997 in Hong Kong. 18 people were infected, of whom 6 died. The outbreak was limited to Hong Kong. All chickens in the territory were slaughtered.

In January 2004, a major new outbreak of H5N1 avian influenza surfaced in Vietnam and Thailand's poultry industry, and within weeks spread to ten countries and regions in Asia, including Indonesia, South Korea, Japan and mainland China. Intensive efforts were undertaken to slaughter chickens, ducks and geese (over 40 million chickens alone were slaughtered in high-infection areas), and the outbreak was contained by March, but the total human death toll in Vietnam and Thailand was 23 people. In February 2004, avian influenza virus was detected in pigs in Vietnam, increasing fears of the emergence of new variant strains.

Fresh outbreaks in poultry were confirmed in Ayutthaya and Pathumthani provinces of Thailand, and Chaohu city in Anhui, China, in July 2004.

In North America, the presence of avian influenza was confirmed at several poultry farms in British Columbia in February 2004. As of April 2004, 18 farms have been quarantined to halt the spread of the virus. Two cases of humans with avian influenza have been confirmed in that region.

In August 2004 avian flu was confirmed in Kampung Pasir, Kelantan, Malaysia. Two chickens were confirmed to be carrying H5N1. As a result Singapore has imposed a ban on the importation of chickens and poultry products. Similarly the EU has imposed a ban on Malaysian poultry products. A cull of all poultry has been ordered by the government within a 10km radius of the location of this outbreak.

An outbreak of avian influenza in January 2005 affected 33 out of 64 cities and provinces in Vietnam, leading to the forced killing of nearly 1.2 million poultry. Up to 140 million birds are believed to have died or were killed because of the outbreak. As of April 17, the outbreak had claimed at least 50 human lives - most in Vietnam.

Vietnam and Thailand have seen several isolated cases where human-to-human transmission of the virus has been suspected. In one case the original carrier, who received the disease from a bird, was held by her mother for roughly 5 days as the young girl died. Shortly afterwards, the mother became ill and perished as well. In March, 2005 it was revealed that two nurses who had cared for avian flu patients have tested positive for the disease.

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